Baseline Predictors of Health-Related Quality of Life After Anterior Cruciate Ligament Reconstruction

There is sparse literature regarding the prognosis and predictors of anterior cruciate ligament (ACL) reconstruction outcomes at six years as measured by validated patient-based outcome instruments and assessed by multivariable analysis. Knowing prognostic information would be valuable in physician counseling of patients considering ACL reconstruction.

Large sample sizes with adequate follow-up are necessary for such analysis. A previously published randomized controlled trial had an enrollment of 225 patients1, which limits risk factor analysis. A previous cohort study utilizing multivariable analysis was limited by 69% follow-up and the lack of baseline measurements of the outcomes2, which are important to adjust for, as they are often the strongest predictor of follow-up scores.

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